The basic research is complete, the findings have been published in the top science journals and Phase 1 of the clinical trials have started. This is an exciting opportunity for YOU to participate in the MISSION! Foundations, corporations or individuals with a philanthropic interest have the opportunity to participate in bringing an end to this disease. This site is dedicated for the support of a Phase II & III clinical trial at Massachusetts General Hospital targeted at a potential to cure people with Type 1 Diabetes. The information is structured to provide background on the protocol and provide an overview of the FDA clinical trial process. It is an opportunity to make a difference by supporting the work directly. Here are some facts regarding Type 1 Diabetes: The cause of Type 1 Diabetes (also known as "childhood", "juvenile" or "insulin-dependent" diabetes) is not known.
There is no known prevention for Type 1 Diabetes.
Medical costs attributed to Diabetes include $27 billion for care to directly treat diabetes, $58 billion to treat the portion of diabetes-related chronic complications that are attributed to Diabetes, and $31 billon in excess general medical costs. Source: American Diabetes Association, 2007 Report
- The National Institutes of Health (NIH) reports that more than 1 million children and teenagers (age 19 and younger) have type 1 diabetes.
- According to the NIH, 5 percent to 10 percent of diagnosed diabetes cases in the United States are type 1 diabetes.
Type 1 diabetes is regarded as an autoimmune disease because a person's immune system's T cells attack and destroy the beta cells in the pancreas that produce insulin. Symptoms of type 1 diabetes usually develop over a short period of time and include increased thirst, frequent urination, constant hunger, weight loss, blurred vision and extreme fatigue. People with type 1 diabetes require numerous daily injections of insulin to survive. After several years researching a cure for Type 1 Diabetes using islet transplantation, Dr. Denise Faustman, Associate Professor at Harvard Medical School and a Researcher at Massachusetts General Hospital, has demonstrated the potential protocol to work for people who already have Type 1 Diabetes. She has now begun a clinical trial based on the protocol that worked in mice. Dr. Faustman maintains her own website at www.faustmanlab.com |